The objective of the research was to quantify the results of milk quota abolition for the milk producers in Poland regarding regional differentiation. The partial equilibrium model CAPRI (Common Agricultural Policy Regionalised Impact) was utilized to analyze the impact of changes in milk quota regime on agri-food sector. Two different scenarios of the intervention on milk market were analyzed. The first one, according to EU Commission outlines, assumes the abolition of milk quota regime in 2015, while the second one its continuation. The simulation conducted in the research proves that irrespective of the scenario the milk production, efficiency and herd size at the country level would achieve similar values. However there would be significant regional discrepancies. The abolition of the milk quota regime would lead to consolidation of the existing production structures and straightening of the polarization process. The overall increase in efficiency of milk production would come together with the deepening of development differences in milk production sector between the regions. The continuation of milk quoting would lead to relatively faster increase of the production in currently worse developed regions than in the regions with higher milk production indexes values. The results prove that in Polish condition the milk quota regime leads to equalize the milk production structures at the country level.